Latest publications

Detection of Microbial Contamination in Nanomaterials Using LAL, rFC and Cell-Based Assays: Implications for Nanotoxicological Hazard Assessment 13 January 2026

Abstract Accurate detection of microbial contamination is essential in the assessment of toxicological and immunological responses to various materials, as low-level contaminants can lead to confounding results. Traditional endotoxin testing...

Comparison of Lung Inflammatory and Transcriptional Responses in Mice and Rats Following Pulmonary Exposure to a Fiber Paradigm-Compatible and Non-Compatible MWCNT 6 October 2025

Abstract IInhalation of multi-walled carbon nanotubes (MWCNTs) poses potential health risks due to their structural similarity to asbestos and their ability to induce chronic lung inflammation, fibrosis, and lung cancer...

nanoPASS Newsletter - June 2025 14 July 2025

The June 2025 edition of the nanoPASS Newsletter highlights groundbreaking research from our Helmholtz Munich partners on carbonaceous particle exposure and chronic lung disease, revealing how SPP1+ macrophages contribute to...

[Poster] AOP302: Lung Surfactant Inhibition as a Predictor for Lung Toxicity 14 July 2025

Research Team: Jorid B. Sørli, Sreyoshee SenguptaInstitution: National Research Centre for the Working Environment, Copenhagen, DenmarkContact: jbs@nfa.dk This research poster presents AOP302, an innovative Adverse Outcome Pathway that establisheslung surfactant...

[Poster] AOP237: Particle-Induced Acute Phase Response Leading to Atherosclerosis 14 July 2025

Research Team: Ulla Vogel, Claudia T. Gutierrez, Jorid B. Sørli, Pernille H. Danielsen, Niels Hadrup, Anne T. SaberInstitution: National Research Centre for the Working Environment, Copenhagen, Denmark This research poster...

UANanoDock: A Web-Based UnitedAtom Multiscale Nanodocking Tool for Predicting Protein Adsorption onto Nanoparticles 3 April 2025

Abstract UANanoDock is a web-based application with a graphical user interface designed for modeling protein–nanomaterial interactions, accessible via the Enalos Cloud Platform (https://www.enaloscloud.novamechanics.com/compsafenano/uananodock/). The application’s foundation lies in the UnitedAtom...

Carbonaceous particle exposure contributes to chronic lung disease development 10 March 2025

A recent study by nanoPASS partner Helmholtz Munich, led by Lianyong Han, Verena Haefner, Ali Önder Yildirim, Heiko Adler, and Tobias Stoeger, explores the role of carbonaceous particle exposure in...

December 2024 Newsletter 11 December 2024

The latest nanoPASS newsletter reflects on key achievements and advancements in nanosafety over the past six months. Highlights include groundbreaking research on environmental triggers for Alzheimer’s disease, insights into nanoparticle...

NPCoronaPredict: A Computational Pipeline for the Prediction of the Nanoparticle–Biomolecule Corona 14 November 2024

In a recent Journal of Chemical Information and Modeling article, Ian Rouse, David Power, Julia Subbotina, and Vladimir Lobaskin from University College Dublin present new computational models to predict nanoparticle...

Acute, controlled inhalation of thin graphene oxide nanosheets in humans with null cardiorespiratory effects 14 November 2024

In a recent Nature Nanotechnology article, Ulla Vogel from the National Research Centre for the Working Environment (NFA) examines the complex ways nanoparticles interact with the immune system, underscoring both...

The eATP/P2×7R Axis Drives Quantum Dot-Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation 14 November 2024

A new study from Helmholtz Munich scientists, Markus Rehberg and Tobias Stoeger, partners in the nanoPASS project, reveals how certain nanoparticles can impact our lungs’ immune response. Published in Advanced...

June 2024 Project Newsletter 14 November 2024

Discover the latest developments in the nanoPASS project, including key advancements and insights from our mid-year activities. This issue covers recent progress, collaborations, and our focus areas for the coming...

AOP173 Substance interaction with the pulmonary resident cell membrane components leading to pulmonary fibrosis 14 November 2024

The first nanomaterial-relevant Adverse Outcome Pathway (AOP) has been endorsed by the OECD, referred to as  as AOP173. AOP173 on ‘Substance interaction with the pulmonary resident cell membrane components leading...

December 2023 Project Newsletter 14 November 2024

Catch up on the latest nanoPASS project updates and insights as we wrap up the year! In this issue, you'll find highlights on recent project milestones, progress in our research,...

Computational modelling of bionano interface 14 November 2024

AbstractThe interface between inorganic and biological materials plays a crucial role in vital technological applications ranging from food processing and cosmetics to medicine but presents enormous technical challenges for computational...

Welcome to nanoPASS: First newsletter 14 November 2024

Our first newsletter is out! Find out what we have been up to for the first few months of the project and discover what is coming up. Read the full...

Particulate Matter Constituents Trigger the Formation of Extracellular Amyloid β and Tau-containing Plaques and Neurite Shortening In Vitro 14 November 2024

AbstractAir pollution is an environmental factor associated with an increased risk of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, characterized by decreased cognitive abilities and memory. The limited models of...