nanoPASS Research Highlighted at the Second Harmonisation Workshop

The Second Harmonisation & Standardisation of Test Methods for Nanomaterials and Advanced Materials Workshop, held virtually on November 18-19, 2024, provided a collaborative forum for advancing testing methodologies and regulatory frameworks for nanomaterials. A key contribution came from Dr. Janez Štrancar, representing Infinite Biotech, a partner in the nanoPASS project, whose work on Mode-of-Action (MoA) determination and long-term hazard assessment was a focal point of the event.

Dr. Štrancar presented an innovative approach to understanding how nanomaterials interact with biological systems over time. By identifying specific biological pathways and biomarkers affected by nanomaterial exposure, his method enables researchers to predict potential long-term health risks. This framework, grounded in Mode-of-Action determination, allows for a detailed analysis of how biological changes evolve, offering significant improvements in the accuracy and reliability of nanosafety assessments.

A core aspect of this approach is its alignment with New Approach Methodologies (NAMs), reducing the reliance on animal testing. Dr. Štrancar emphasized the value of linking in vitro findings with clinical and epidemiological data, demonstrating how predictive models can translate laboratory results into real-world safety insights.

nanoPASS and the Future of Nanomaterials Testing

Dr. Štrancar’s presentation exemplifies the nanoPASS project’s commitment to developing advanced, standardized testing methods that address the complexities of nanomaterials. Infinite Biotech, alongside other nanoPASS partners, is driving progress in harmonizing testing protocols and ensuring that innovative materials are assessed with both scientific rigor and practical applicability.

The contributions of nanoPASS partners, including this pivotal research, underscore the project’s role in bridging the gap between cutting-edge science and regulatory frameworks. This alignment is crucial for the safe integration of nanomaterials across industries.